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Standards management for biobanks and blood banks

Keep specimen metadata aligned as coding systems, terminologies and clinical classifications evolve.

Coding systems evolve over time

Biobanks register specimens using the classifications, code systems and controlled terminologies that were valid when each sample was stored — often spanning LOINC, SNOMED CT, ICD and national releases.

Network of connected terminology standards used in biobank metadata

Metadata reflects the moment of storage

When specimens are collected on different dates, their associated metadata likely encodes values from different standard versions — creating semantic drift across the collection.

LOINC terminology relationships across standard versions

Central management enables upcoding

When code systems and terminologies are managed centrally, biobanks can update specimen metadata to current releases — supporting interoperability and FAIR-oriented metadata practices.

Expanded LOINC graph after centralized standards update

The standards drift problem

Specimens are stored today, but reused years later under newer standards. Metadata encoded at collection time may no longer align with current coding systems — making search, pooling and reuse harder than it should be.

What changes over time

  • ICD-10, LOINC, SNOMED CT and national editions such as ICD-10-GM
  • Alpha-ID-SE, local taxonomies and project-specific codelists
  • Release frequency that can exceed once per year for active terminologies

How DataSDR helps

  • Central catalog with version history and governed releases
  • Mapping and review queues for metadata harmonization
  • Release packages and API delivery to downstream systems

Outcome

Better discoverability, interoperability, provenance and reuse of specimen-associated metadata — with traceability as standards evolve.

Adapted from: Through the effective implementation of standards in the data acquisition, coding and management process, the quality and thereby confidence in data integrity is improved. Furthermore, standardization enables…

Read full citation →

Sánchez-López AM et al. J Pers Med. 2024;14(7):668. doi: 10.3390/jpm14070668

Terminology exploration

DataSDR supports multi-language version control across LOINC and SNOMED CT, helping biobanks with international networks maintain semantic interoperability. The screenshots below use the English edition.

Metadata quality for biobanking workflows

Biobanks depend on high-quality biological material and associated data. DataSDR focuses on the metadata layer: terminology versioning, provenance, mappings, auditability and reuse.

FAIR principles — Findable, Accessible, Interoperable and Reusable — provide a useful orientation for metadata design. DataSDR is designed to support those goals without claiming ISO 20387 or FAIR certification on your behalf.

Contact us

Please contact us if your organization has a data management challenge you need assistance with.